Inspired by true events, follows childhood leukemia survivor Joanna Gold as she chases her lifelong dream of becoming a home shopping channel host. Shedding her "cancer girl" label, she moves away from her parents, starts a budding romance for the first time in her adult life and befriends her idol, the charismatic star of the network. But when a little white lie to her boss turns into a big snowy avalanche, Joanna finds that living the dream comes with a hefty price tag.